Product description
CDw17 is an intermediate glycosphingolipid from the metabolism of higher gangliosides that localizes to sphingolipid-sterol rafts. CDw17 is found on monocytes, granulocytes, basophils, platelets, a subset of peripheral B-cells (CD19+) and tonsil dendritic cells. It is rapidly down regulated on activated granulocytes and is upregulated on IL-2 activated T-lymphocytes. CDw17 binds to bacteria and may function in phagocytosis. It may also be involved in angiogenesis. Aberrant levels of glycosphingolipids are a feature of cancer cells and may influence integrin clustering and internalization. Positive control: Human PBL and tonsil.
Specifications
Host
Mouse
Clonality
Monoclonal
Clone
EBS-CD-014
Supplier
PROGEN
Shipping & storage
Shipping condition
Room Temperature
Storage temperature
2-8°C

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anti-CDw17 mouse monoclonal, EBS-CD-014, purified

691621

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anti-CDw17 mouse monoclonal, EBS-CD-014, purified

691621

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