anti-CD84 mouse monoclonal, 152-1D5, purified

152-1D5 reacts with human CD84 (Mw 74 kDa). CD84 is expressed on mature B-cells and on B-cell lines but not on plasma cell lines. Immunohistochemistry demonstrated that it strongly stains tissue macrophages. It is also expressed on platelets and at low levels on blood T-cells. It is a highly N-glycosylated protein and belongs to immunoglobulin superfamily. It may play a role in leukocyte activation but cellular expression does not significantly increase after activation. 152-1D5 was clustered at the Vth WLDA. Positive control: Raji, HL60, THP-1, HMC-1, HEL and NAMALWA cells. Human platelets, macrophages and human tonsil.