Product description
197-2B1 reacts with human CD46, a 52-58 kDa single chain type 1 transmembrane molecule. CD46 is a cofactor for the factor I regulation of complement components C3b and C4b and contains four N-terminal short consensus repeat (SCR) modules. It is strongly expressed on salivary gland ducts and kidney ducts and often increased on tumor cells. It is also serves as a measles virus receptor, an adherence factor for group A Streptococcus pyogenes, and a cellular pilus receptor for pathogenic Neisseria. 197-2B1 has been clustered at the VIth HLDA Workshop. Positive control: K562, U937, HL60, HeLa and Jurkat cells, and human lymphocytes. Lymph node and tonsil.
Specifications
Applications
FC, IHC, ICC
Host
Mouse
Clonality
Monoclonal
Clone
197-2B1
Supplier
PROGEN
Shipping & storage
Shipping condition
Room Temperature
Storage temperature
2-8°C

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anti-CD46 mouse monoclonal, 197-2B1, purified

691589

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anti-CD46 mouse monoclonal, 197-2B1, purified

691589

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