anti-Cytokeratin 19, Ks19.10, supernatant, IgG1
Ks 19.10 represents a sensitive marker to discriminate glandular epithelia (and tumors derived therefrom) from those of different origin. No reaction with hepatocellular CA! Tumors specifically detected: All adeno-CA tested; cholangio CA of liver; renal cell CA, transitional cell CA of bladder; ovary CA; squamous cell CA of cervix, bronchus and lung (intermediate type); carcinoid tumor of bronchus; mammary CA. Polypeptide reacting: Mr 40 000 polypeptide (keratin K19; formerly also designated cytokeratin 19) of human glandular epithelia.Reactivity on cultured cell lines: MCF-7, negative on PLC.
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