Sheep anti methotrexate antibody recognizes Methotrexate, a drug originally manufactured as a chemotherapeutic agent for the treatment or a number of cancers. Methotrexate also acts as a disease-modifying anti-rheumatic drug used for the treatment of autoimmune conditions such as rheumatoid arthritis, Chron's disease and vasculitis.Sheep anti methotrexate antibody exhibits the following cross reactivities with related compounds:-
Aminopterin | 18% |
Folic acid | <0.01% |
Dyhydrofolic acid | <0.01% |
Tetrahydrofolic acid | <0.01% |
N-5-Methyltetrahydrofolic acid | <0.01% |
Folinic acid | <0.01% |
N-(p-Aminobenzoyl)-L-glutamic acid | <0.01% |