Calprotectin is a functional heterocomplex of small EF hand calcium binding proteins S100A8 and S100A9. The heterocomplex is expressed in various cells and tissues and induced upon inflammation. The complex is released by neutrophilic granulocytes in inflammatory disorders such as inflammatory bowel disease and rheumatoid arthritis. Released Calprotectin serves as a leukocyte chemoattractant and modulates inflammation via damage receptors. Via it's binding to the receptor of advanced glycation end-products (RAGE), calprotectin is implicated in chronic inflammation and was also linked to cancer formation. Tissue expression: strong expression in myeloid cells and psoriatic keratinocytes.
Productname
anti-Calprotectin - S100A8/A9 Complex , mouse monoclonal, clone 69-6-1
610191
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Productname
anti-Calprotectin - S100A8/A9 Complex , mouse monoclonal, clone 69-6-1
610191
By filling out this form, you request a sample. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.
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