DNA/RNA Oxidative Damage (Clone 7E6.9) ELISA Kit
DNA and RNA are damaged by oxidation during aging and in a variety of disease states including cancer.{22083,22087,22086} Guanine is the base is most prone to oxidation, and the repair processes initiated to correct the damage release multiple oxidized guanine species into the urine, including 8-hydroxyguanosine (8-OHG), 8-hydroxy-2’-deoxyguanosine (8-OHdG), and 8-hydroxyguanine. Some commercial vendors offer immunoassays that detect only 8-OHdG. Cayman's DNA/RNA Oxidative Damage (Clone 7E6.9) ELISA Kit is a competitive assay that can be used to measure both 8-OHdG and 8-OHG. Since the antibody used in the assay recognizes damaged nucleic acid species other than 8-OHdG, the value obtained with our assay will be higher than that obtained by competitor ELISAs or by LC/MS analysis that measure a single species. As such, caution is recommended when comparing results obtained from this kit to those obtained by other methods.
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DNA/RNA Oxidative Damage (Clone 7E6.9) ELISA Kit
501130-480
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DNA/RNA Oxidative Damage (Clone 7E6.9) ELISA Kit
501130-480
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