FABP6 Rabbit Monoclonal Antibody (Clone 201)
Fatty acid-binding protein 6 (FABP6) is a member of the intracellular lipid-binding protein (iLBP) family with a role in bile acid homeostasis.{65342,65343} It is composed of 10 antiparallel ?-strands, which form a ?-barrel containing a lipid binding site and is expressed primarily in enterocytes of the ileum, and to a lesser extent in the adrenal gland, ovaries, and stomach.{65344,65345,65342} FABP6 binds bile acids and fatty acids and interacts with the ileal bile acid transporter to aid in bile acid uptake and facilitate intracellular trafficking of bile acids.{65342} Fabp6 knockdown induces dietary fat malabsorption, decreased bile acid reabsorption, and a sex-specific increase in adiposity in mice fed a Western diet.{65346} Serum levels of FABP6 are increased in patients with colorectal cancer and decrease following surgical removal of cancerous tissues.{65347} FABP6T79M is associated with a decreased risk of type 2 diabetes in obese individuals.{65348} Cayman’s FABP6 Rabbit Monoclonal Antibody (Clone 201) can be used for flow cytometry (FC), immunocytochemistry (ICC), and immunofluorescence (IF) applications.
Do you have any questions about this product?
Order your product by email
Productname
FABP6 Rabbit Monoclonal Antibody (Clone 201)
37084-50
By filling out this form, you are placing an order by e-mail. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.
Request a sample
Productname
FABP6 Rabbit Monoclonal Antibody (Clone 201)
37084-50
By filling out this form, you request a sample. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.
Are you looking for specific products, alternatives or documentation?
