Legenda image
Formalin-fixed, paraffin-embedded human Tonsil stained with Cdk1 Mouse Monoclonal Antibody (A17.1.1).
Product description
Recognizes a 34kDa protein (cdk1), identified as p34cdc2 (a catalytic subunit of Maturation Promoting Factor). Its epitope maps near the C-terminus of the protein and its core is thoµght to be LGTPNNEV (aa220-227 in murine cdc2). It shows no cross reaction with cdk2 p32. It supports the kinase activity. p34cdc2 plays a crucial role during cell division and is most active during mitosis. It is a serine/threonine kinase, which is activated by cyclin, by dephosphorylation of tyrosine residues. p34cdc2 is inactivated by a tyrosine kinase. This MAb reportedly inhibits the activation of p34cdc2 kinase by cyclins.
Specifications
Applications
IP, IHC, WB, IF
Host
Mouse
Clonality
Monoclonal
Clone
A17.1.1
Isotype
Mouse IgG2a, kappa
Supplier
Abeomics
Shipping & storage
Storage temperature
2-8°C

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Anti-Cdk1 / p34cdc2 Serine-Threonine Kinase Monoclonal Antibody(Clone: A17.1.1)

36-3669

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Productname

Anti-Cdk1 / p34cdc2 Serine-Threonine Kinase Monoclonal Antibody(Clone: A17.1.1)

36-3669

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