Human chorionic gonadotropin (hCG) is glycoprotein hormone secreted during pregnancy that has important roles in the maintenance of pregnancy.{52901,52902} It exists as a heterodimer that is composed of two subunits, hCG? and hCG?, that are subject to glycosylation, generating a variety of glycosylated hCG variants that have distinct biological functions.{52903,52904} The expression of genes encoding hCG? and hCG? are regulated by a variety of hormones, growth factors, and cytokines.{52904} It is secreted by placental trophoblasts during early pregnancy and serum hCG levels peak from gestational weeks 7 to 10.{52901} hCG has numerous roles in pregnancy, including stimulating production of progesterone from the corpus luteum and promoting angiogenesis of uterine vasculature and the growth of fetal organs.{52905} Urinary hCG levels have been commonly used in the determination of pregnancy.{52901} Increased serum, urinary, or tumor levels of hCG? have been found in patients with a variety of cancers, including bladder, lung, cervical, or ovarian cancer, and are associated with poor prognosis.{52906} Cayman's hCG Rabbit Monoclonal Antibody can be used for ELISA, immunohistochemistry (IHC), and Western blot (WB) applications. This antibody recognizes the hCG? subunit in both the monomeric and hCG?? heterodimeric forms.
Productname
hCG Rabbit Monoclonal Antibody
32267-100
By filling out this form, you are placing an order by e-mail. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.
Productname
hCG Rabbit Monoclonal Antibody
32267-100
By filling out this form, you request a sample. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.
Are you looking for specific products, alternatives or documentation?