CD79a (C-Term) Rabbit Monoclonal Antibody
CD79a is a member of the heterodimeric signal transduction component of the B cell receptor (BCR) complex that is encoded by CD79A/MB-1 in humans.{54536} It is composed of a disulfide-linked extracellular domain, a transmembrane region, and a cytoplasmic tail containing an immunoreceptor tyrosine-based activation motif that facilitates intracellular signaling.{54536,54537} CD79a is expressed exclusively in B cells and B cell progenitors, and is commonly used as a B cell marker. It is co-expressed at the cell surface with CD79b and immunoglobulins of all isotypes as the mature BCR complex.{54536} Mutations in CD79A/MB-1 have been found in patients with autosomal recessive agammaglobulinemia.{54538} Cayman's CD79a (C-Term) Rabbit Monoclonal Antibody can be used for immunohistochemistry (IHC) and Western blot (WB) applications.
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CD79a (C-Term) Rabbit Monoclonal Antibody
32243-100
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CD79a (C-Term) Rabbit Monoclonal Antibody
32243-100
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