Histone H3K9Me3/S10Ph Monoclonal Antibody
Histone H3 is a nuclear protein and a component of the nucleosome core, a basic unit of chromatin, that is essential for organizing genomic DNA in eukaryotic nuclei.{57056} It is a globular protein that contains an unstructured N-terminal tail that extends outside of the nucleosome core and is subject to various post-translational modifications (PTMs), including methylation, phosphorylation, acetylation, and citrullination.{57056,53978} Trimethylation of lysine 9 and phosphorylation of serine 10 on histone H3 (H3K9Me3/S10Ph) is associated with repression of polycomb-regulated genes in differentiated mesenchymal stem cells (MSCs) and resting B cells but not pluripotent embryonic stem cells (ESCs).{60015} Cayman's H3K9Me3/S10Ph Monoclonal Antibody recognizes histone H3 only when modified by both trimethylation at K9 and phosphorylation at S10. This antibody can be used for ELISA, multiplex-based assay, and Western blot (WB) applications.
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Histone H3K9Me3/S10Ph Monoclonal Antibody
32168-100
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Histone H3K9Me3/S10Ph Monoclonal Antibody
32168-100
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