Histone H4 is one of four core histone proteins that are involved in the organization of DNA into chromatin.{18136} Histones are globular proteins with unstructured N-terminal tails and are subject to a variety of post-translational modifications, such as methylation, acetylation, phosphorylation, and citrullination, that can influence chromatin structure and regulate gene transcription.{18136,57056} Phosphorylation of histone H4 at serine 1 (H4S1Ph) is increased during the S-phase and mitosis in HeLa cells, C. elegans, and Drosophila, as well as during spermatogenesis in mice.{54369,54370} MG-63 cells expressing a serine-to-alanine substitution at Ser1 in histone H4, which abolishes its phosphorylation, have reduced markers of autophagy. Cayman's Histone H4S1Ph Monoclonal Antibody can be used for ELISA, immunocytochemistry (ICC), multiplex-based assays, and Western blot (WB) applications.
Productname
Histone H4S1Ph Monoclonal Antibody
32154-100
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Productname
Histone H4S1Ph Monoclonal Antibody
32154-100
By filling out this form, you request a sample. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.
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