Glutamic acid decarboxylase 65 (GAD65), also known as GAD2, catalyzes the production of GABA from L-glutamic acid and is encoded by GAD2 in humans.{61314} It is primarily expressed in pancreatic islets but is also expressed in neurons of the central and peripheral nervous systems and is localized to vesicular membranes.{61314} Autoantibodies against GAD65 have been found in patients with type 1 diabetes mellitus or gestational diabetes mellitus and have been used as biomarkers of type 1 diabetes mellitus.{61314} GAD65 autoantibodies have also been found in patients with the rare neurological disorder stiff-man syndrome or autoimmune epilepsy.{61315,57555} Cayman’s GAD65 Monoclonal Antibody (Clone 9B10) can be used for ELISA and Western blot (WB) applications. The antibody recognizes GAD65 at 65.4 kDa from human and mouse samples.
Productname
GAD65 Monoclonal Antibody
31360-100
By filling out this form, you are placing an order by e-mail. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.
Productname
GAD65 Monoclonal Antibody
31360-100
By filling out this form, you request a sample. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.
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