Legenda image
Flow cytometry surface staining pattern of murine bone marrow cell suspension stained using anti-mouse CD160 (429) purified antibody (azide free, concentration in sample 0,19 µg/ml) DAR APC.
Product description
CD106 / VCAM-1 (vascular cell adhesion molecule-1) is an Ig-like cell surface adhesion molecule binding VLA-4 integrin. VCAM-1 is a potent T cell costimulatory molecule taking part in their positive selection and survival, as well as in adhesion, transendothelial migration and activation of peripheral T cells. VCAM-1 is also involved in endothelial cell-cell contacts. Whereas VCAM-1 normally mediates leukocyte extravasion to sites of tissue inflammation, tumour cells can use overexpressed VCAM-1 to escape T cell immunity.Specificity : The rat monoclonal antibody 429 (also known as MVCAM.A) recognizes an extracellular epitope of murine CD106, a 100-110 kDa type I membrane protein of the immunoglobulin superfamily, a crucial mediator of leukocyte adhesion, and a costimulation molecule.
Specifications
Applications
FC, IP, IHC-Fr, FUNC
Clonality
Monoclonal
Clone
429 (MVCAM.A)
Isotype
Rat IgG2a kappa
Supplier
Abeomics
Shipping & storage
Storage temperature
2-8°C

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Anti-Mouse CD106 Azide Free Antibody (Clone : 429 (MVCAM.A))

30-2664

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Anti-Mouse CD106 Azide Free Antibody (Clone : 429 (MVCAM.A))

30-2664

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