Legenda image
Surface staining of CD137 in PHA activated PBMC with anti-CD137 (4B4-1) PE.
Product description
CD137, also known as TNFRSF9 or 4-1BB, is an inducible costimulatory molecule expressed mainly on activated T cells. Its ligand, known as 4-1BBL, is expressed on activated macrophages, mature B cells, hematopoietic stem cells, and myeloid progenitor cells. CD137 signaling leads to maintaining the survival of activated T cells and CD8+ memory T cells, and clonal expansion of T cells, but also to suppressing myelopoiesis and dendritic cell development. Triggered CD137 induces a cytokine release profile regulating peripheral monocyte survival. Soluble forms of CD137 may provide negative control mechanism for some immune responses.
Specifications
Applications
FC, IP, ELISA, FUNC
Host
Mouse
Clonality
Monoclonal
Clone
4B4-1
Isotype
Mouse IgG1
Supplier
Abeomics
Shipping & storage
Shipping condition
Blue Ice
Storage temperature
2-8°C

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Anti-CD137 / 4-1BB Monoclonal Antibody (Clone:4B4-1)-PE Conjugated

30-2121

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Anti-CD137 / 4-1BB Monoclonal Antibody (Clone:4B4-1)-PE Conjugated

30-2121

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