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Anti-Notch 1 Monoclonal Antibody (Clone:mN1A)
30-1459
0,1 mg
€614
Legenda image
Intracellular staining of Notch1 in Jurkat cells using anti-Notch1 (mN1A) purified.
Product description
Notch 1 is a 270-300 kDa transmembrane heterodimeric protein with multiple extracellular growth factor-like repeats, and with an intracellular domain consisting of multiple different domain types. It serves as a receptor for membrane ligands, such as Delta 1, Jagged1 (CD339), and Jagged2, and regulates cell fate decisions. Upon ligand binding the transmembrane form of Notch 1 is repeatedly cleaved to provide approximately 120 kDa Notch intracellular fragment (NICD), which translocates to the nucleus and acts as a part of transcriptional complexes that alter differentiation, proliferation, and apoptosis. The highest level of Notch 1 expression is in brain, lung and thymus.
Specifications
Applications
FC, IP, IHC-Fr, WB, ICC
Host
Mouse
Clonality
Monoclonal
Clone
mN1A
Isotype
Mouse IgG1
Supplier
Abeomics
Shipping & storage
Shipping condition
Blue Ice
Storage temperature
2-8°C
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Anti-Notch 1 Monoclonal Antibody (Clone:mN1A)
30-1459
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Anti-Notch 1 Monoclonal Antibody (Clone:mN1A)
30-1459
By filling out this form, you request a sample. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.
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