Polyclonal antibody to NALP4 (PAN-2)
This antibody recognizes NALP4; human NALP4 is a 994 amino acid protein. NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP4, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1) via their involvement in multiprotein complexes called inflammasomes.
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Polyclonal antibody to NALP4 (PAN-2)
20-1079
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Polyclonal antibody to NALP4 (PAN-2)
20-1079
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