Myosmine

(±)-Nicotine (Item No. 16535) is the racemic mixture of the dominant alkaloid found in tobacco plants. It acts as an agonist at neuronal nicotinic acetylcholine receptors (Kis = 481 and 11.1 nM for ?3?4 and ?4?2 subtypes, respectively) and possesses addictive and teratogenic properties.{18814} Myosmine is a minor tobacco alkaloid that is structurally related to nicotine. It can also be found in a variety of other plants that are commonly eaten, including maize, rice, and potato.{29066} Myosmine weakly binds to neuronal acetylcholine receptors (Ki = 3.3 µM).{29064} However, it can be nitrosated, giving rise to a DNA adduct.{29066,29067,29065}