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sPLA2 (human Type V) Monoclonal Antibody (Clone MCL-3G1)
160510-100
100 ug
€387
Product description
Phospholipase A2 (PLA2) catalyzes the hydrolysis of fatty acids at the sn-2 position of glycerophospholipids. PLA2 (type V) is a secretory PLA2 (sPLA2) of approximately 14 kDa and is one of the isoforms in the growing list of the PLA2 enzyme family.{3506} This enzyme, rather than the sPLA2 (type II), is responsible for arachidonic acid mobilization leading to prostaglandin production in macrophages and mast cells.{3941,4455,4053,8454} Consistent with this role, sPLA2 (type V) is associated with the golgi apparatus, nuclear envelope, and plasma membrane in murine bone marrow-derived mast cells.{7627} sPLA2 (type V) has been cloned from a variety of species including human, mouse, and rat.{7748,5754,7749} The enzyme is expressed in heart, lung, placenta, and spleen, as well as P388D1 macrophages and mast cells.{3941,4455,7749}
Specifications
Applications
WB, ELISA
Host
Mouse
Clonality
Monoclonal
Clone
MCL-3G1
Isotype
IgG1
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C
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sPLA2 (human Type V) Monoclonal Antibody (Clone MCL-3G1)
160510-100
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sPLA2 (human Type V) Monoclonal Antibody (Clone MCL-3G1)
160510-100
By filling out this form, you request a sample. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.
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