Idebenone

Idebenone is a benzoquinone analog of coenzyme Q10 (Item No. 11506), a natural quinone that serves as a cofactor in the electron transport chain in mitochondria.{20672,20670} Like coenzyme Q10, idebenone is a potent lipid antioxidant that prevents the generation of free radicals.{20672,25233} In particular, idebenone targets mitochondria, preserves mitochondrial function, and confers cytoprotection.{25236,25231,25232} In this way, idebenone has neuroprotective effects and has applications in Friedreich ataxia.{25235,25234}