Product description

LY2584702 is an inhibitor of p70 ribosomal S6 kinase (p70S6K; IC50 = 0.004 µM).{30512} It is selective for p70S6K over a panel of 83 kinases. LY2584702 inhibits the phosphorylation of S6 in HCT116 colon cancer cells (IC50 = 0.1-0.24 µM) and decreases triglyceride levels and apolipoprotein B secretion in tuberous sclerosis complex 2 (TSC2) knockdown HepG2 cells.{30512,30511} It suppresses self-renewal of primary mouse bone marrow stromal cells when used at a concentration of 2 µM.{62585} LY2584702 reduces tumor growth in an HCT116 colon cancer mouse xenograft model (ED50 = 2.3 mg/kg).{30512}

Specifications
CAS number
1082949-68-5
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C

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LY2584702 (tosylate)

15320-5

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LY2584702 (tosylate)

15320-5

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