DNQX
DNQX is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.5 and 0.1 ?M for AMPA and kainate receptors, respectively versus IC50 = 40 ?M for NMDA receptors).{23070,23071,23072} This compound has been used to specifically target AMPA and kainate receptor responses and thus differentiate from that of NMDA receptors. DNQX does not stimulate a robust long-term potentiation in the hippocampus.{23069}
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