B-HT 920 (hydrochloride)
B-HT 920 is a potent agonist of dopamine 2 (D2) receptors (Ki = 5.8 nM) that shows selectivity for D2 over D3 and D4 receptors.{34094,34095,34098} It has neuroprotective and regenerative effects in animal models of Parkinson’s disease.{34093} B-HT 920 is also an agonist of ?2-adrenergic receptors and an antagonist of serotonin-3 (5-HT3; Ki = 0.35 µM) receptors.{34096,34097}
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