TC-O 9311 is an agonist of the orphan G protein-coupled receptor GPR139 (EC50 = 39 nM in a calcium mobilization assay).{42984} It is selective for GPR139 over a panel of 90 additional targets. TC-O 9311 (1 ?M) inhibits cell death induced by 1-methyl-4-phenylpyridinium (MPP+), but not 6-hydroxydopamine (6-OHDA; Item No. 25330), in primary dopaminergic midbrain neurons.{42985}
Productname
TC-O 9311
14030-25
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Productname
TC-O 9311
14030-25
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