Product description
I?B? is an ankyrin repeat-containing nuclear protein that is highly homologous to the I?B family member Bcl-3. Transcription of I?B? is upregulated by stimulation with TLR ligands, IL-1, and IL-6 in cultured B-lymphocytes and monocytes/macrophages, but only faintly so in T-lymphocytes, fibroblasts, and endothelial cells. IkBz preferentially associates with the NF-?B subunit p50 rather than p65 and recombinant I?B? proteins inhibit the DNA binding of the p65/p50 heterodimer and the p50/p50 homodimer.
Specifications
Applications
WB
Host
Rabbit
Clonality
Polyclonal
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C

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IkB? Polyclonal Antibody

13926-1

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IkB? Polyclonal Antibody

13926-1

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