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Recombinant anti-human-IL-1 beta Antibody (Canakinumab Biosimilar)
12-9112
100 ug
€551
Legenda image
ELISA plate pre-coated by 1 µg/mL (100 µL/well) Human IL1B Protein, hFc Tag (Abeomics 32-17198) can bind Anti-IL1B Neutralizing antibody (Abeomics 12-9112) in a linear range of 0.61-156.25 ng/mL.
Product description
Target: IL-1 Beta
Generic name: Canakinumab
Product Origin: Recombinant in Human cells
Canakinumab is a recombinant, human anti-human-IL-1beta monoclonal antibody that belongs to the IgG1/beta isotype subclass with a molecular mass of 145157 Daltons when deglycosylated. Canakinumab binds to human IL-1beta2 and neutralizes its inflammatory activity by blocking its interaction with IL-1 receptors, but it does not bind IL-1alpha or IL-1 receptor antagonist (IL-1ra).
References:
1. Church LD, McDermott MF: Canakinumab, a fully-human mAb against IL-1beta for the potential treatment of inflammatory disorders. Curr Opin Mol Ther. 2009 Feb;11(1):81-89.
2. Lachmann HJ, et al.: Use of canakinumab in the cryopyrin-associated periodic syndrome. N Engl J Med. 2009 Jun 4;360(23):2416-25. doi:10.1056/NEJMoa0810787
Specifications
Applications
FC, ELISA, IF, ICC, FUNC
Clonality
Monoclonal
Isotype
human IgG1
Supplier
Abeomics
Shipping & storage
Storage temperature
-20°C
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Recombinant anti-human-IL-1 beta Antibody (Canakinumab Biosimilar)
12-9112
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Recombinant anti-human-IL-1 beta Antibody (Canakinumab Biosimilar)
12-9112
By filling out this form, you request a sample. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.
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