Legenda image
Expi 293 cell line transfected with irrelevant protein (A) and human CD27 (B) were surface stained with Rabbit anti-CD27 monoclonal antibody 1µg/ml (clone: DM57) followed by Alexa 488-conjugated anti-rabbit IgG secondary antibody.
Product description
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.
Specifications
Applications
FC, ELISA
Host
Rabbit
Clonality
Monoclonal
Clone
DM57
Isotype
Rabbit IgG
Supplier
Abeomics
Shipping & storage
Storage temperature
-20°C

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Anti-CD27 antibody(DM57), Rabbit mAb

12-9044

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Anti-CD27 antibody(DM57), Rabbit mAb

12-9044

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