Legenda image
FACS data of serially titrated Rabbit anti-B7H3 monoclonal antibody (clone: DM53) on on Expi 293 cell line transfected with human B7-H3. The Y-axis represents the mean fluorescence intensity (MFI) while the X-axis represents the concentration of IgG used.
Product description
The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Specifications
Applications
FC, ELISA
Host
Rabbit
Clonality
Monoclonal
Clone
DM53
Isotype
Rabbit IgG
Supplier
Abeomics
Shipping & storage
Storage temperature
-20°C

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Anti-B7-H3 antibody(DM53), Rabbit mAb

12-9043

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Anti-B7-H3 antibody(DM53), Rabbit mAb

12-9043

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