Product description
CD243, also known as multidrug resistant protein 1 (MDR-1) or P-glycoprotein (Pgp) is an ATP binding cassette (ABC)-containing efflux transporter for xenobiotic lipophilic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. It is expressed in many tissues, including the brain, liver, pancreas, testes, kidney, and blood (B, T, NK cells, but not monocytes).
Specifications
Applications
FC, IP, IHC-P, IHC-Fr, FUNC
Host
Mouse
Clonality
Monoclonal
Clone
UIC2
Isotype
Mouse IgG2a kappa
Supplier
Exbio
Product status
RUO
Shipping & storage
Storage temperature
2-8°C

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Productname

Anti-Hu CD243 Purified Low Endotoxin

12-764-C100

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Productname

Anti-Hu CD243 Purified Low Endotoxin

12-764-C100

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