Product description

CD42b (GPIb alpha) composes together with GPIb beta, GPIX and GPV the GPIb-IX-V receptor complex critical in the process of platelet-rich thrombus formation by tethering the platelet to a thrombogenic surface. CD42b binds to von Willebrand factor (VWF) exposed at a site of vascular injury, as well as to thrombin, coagulation factors XI and XII, high molecular weight kininogen, TSP-1, integrin Mac-1 and P-selectin. The extracellular domain of CD42b by its interactions also contributes to metastasis.

Specifications
Applications
FC, IP, WB, ELISA, ICC
Host
Mouse
Clonality
Monoclonal
Clone
AK2
Isotype
Mouse IgG1
Supplier
Exbio
Product status
RUO
Shipping & storage
Storage temperature
2-8°C

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Anti-Hu CD42b Purified Low Endotoxin

12-150-C100

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Anti-Hu CD42b Purified Low Endotoxin

12-150-C100

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