Anti-Cytokeratin 10 (KRT10) (Suprabasal Epithelial Marker) Recombinant Rabbit Monoclonal Antibody
This MAb recognizes a protein of 56.5kDa, identified as cytokeratin 10 (CK10). CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of CK10 strictly parallels the extent of differentiation; it is absent in the basal layer, appears in the first suprabasal layers and increases in concentration towards the granular layer. However, CK10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm, clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm, clinical stages II and III), CK10 is detected very frequently. Expression of CK10 is related to maturation of malignant keratinocytes, being preferentially detected in more-differentiated parts.
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Anti-Cytokeratin 10 (KRT10) (Suprabasal Epithelial Marker) Recombinant Rabbit Monoclonal Antibody
12-1151
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Anti-Cytokeratin 10 (KRT10) (Suprabasal Epithelial Marker) Recombinant Rabbit Monoclonal Antibody
12-1151
By filling out this form, you request a sample. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.
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