PRMT4/CARM1 Inhibitor
PRMT4/CARM1 Inhibitor selectively blocks the activity of PRMT4/CARM1 with an IC50 value of 7.1 µM.{19872} It displays very low affinity towards PRMT1 and SET7 with IC50 values of 63 and 943 µM, respectively.{19872} In human prostate cancer LNCaP cells, this compound reduced the prostate-specific antigen promoter activity at 8-10 µM.{19872}
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