Mouse Anti-Human TLR2-APC
The Toll-like receptor (TLR) family is comprised of type I transmembrane proteins characterized by an extracellular leucine-rich domain and a cytoplasmic tail that contains a conserved region call the Toll/IL-1 (TIR) domain. First discovered in Drosophila, TLRs recognize specific molecular patterns that are present in microbial components and respond to these components in order eliminate or limit invading microbes. TLR2 recognizes and is activated by components from a broad variety of microorganisms including lipoproteins from Gram-negative and Gram-positive bacteria, lipoteichoic acid from Gram-positive bacteria, lipoarabinomannan from mycobacteria, and zymosan from yeast. TLR2 has been reported to functionally associate with TLR1 and TLR6 in order to recognize various lipopeptides.
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Mouse Anti-Human TLR2-APC
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