Kruppel-like factor 10 (KLF10 ) is a member of the Kruppel-like family of transcription factors, which are known to be involved in anti-proliferative and apoptotic inducing functions following TGF-beta induction. KLF10 plays an important role in the repression of proliferative and hypertrophic pathways, possibly through the actions of PTTG1 (pituitary tumor-transforming gene 1). KLF10 is found to be predominantly expressed in various tissues and its expression is regulated by cytokines and growth factors. Over-expression of KLF10 has been found to induce apoptosis in pancreatic cancer cells. In addition, KLF10 induces apoptosis via a mechanism which involves the formation of reactive oxygen species.
Productname
Polyclonal Antibody to KLF10
11-8067
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Productname
Polyclonal Antibody to KLF10
11-8067
By filling out this form, you request a sample. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.
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