ASAP3 belongs to Arf-specific GTPase-activating proteins which regulate Arfs by stimulating their intrinsic GTP hydrolysis. This protein contains a catalytic core of a PH (Pleckstrin Homology) domain, a GAP motif, and two ANK (Ankyrin) repeats. ASAP3 also associates with focal adhesions and with cytoplasmic membranes at the circular dorsal ruffles, where the actin skeleton is remodeled. Depletion of ASAP3 by RNA interference suppresses cell migration in wound healing.
Productname
Polyclonal Antibody to ASAP3
11-8066
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Productname
Polyclonal Antibody to ASAP3
11-8066
By filling out this form, you request a sample. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.
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