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Anti-Hu CD160 Purified
11-750-C100
0,1 mg
€167
Product description
CD160 is a cell surface glycoprotein of immunoglobulin superfamily, which functions as a costimulatory receptor expressed mainly on cytotoxic cell populations and recognizing both classical and non-classical MHC class I molecules. It can form disulfide-linked multimers. Down-modulation of CD160 occurs as a consequence of its proteolytic cleavage and the released soluble form was found to impair the MHC-class I specific cytotoxicity of CD8+ T lymphocytes and NK cells. In contrast to GPI-anchored isoform with broader expression among CD160 positive cells, expression of the transmembrane isoform is restricted to NK cells and is activation-dependent.
Specifications
Applications
FC, IP
Host
Mouse
Clonality
Monoclonal
Clone
BY55
Isotype
Mouse IgM kappa
Supplier
Exbio
Product status
RUO
Shipping & storage
Storage temperature
2-8°C
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Anti-Hu CD160 Purified
11-750-C100
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Anti-Hu CD160 Purified
11-750-C100
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