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Anti-Drebrin Purified
11-694-C100
0,1 mg
€231
Product description
Drebrin is an actin-binding protein, which is expressed mainly in neurons and plays important role in their morphogenesis. The highest level of its expression is in developing brain. Both in neurons and non-neuronal cells drebrin acts as a key regulator of actin cytoskeleton remodelling, affecting especially intercellular junctions, such as dendritic spines of neurons or the immune synapses of T cells. Decrease of drebrin amount in the brain seems to be associated with Alzheimer's disease and Down syndrome, and in case of B-cell precursor acute lymphoblastic leukemia (BCP-ALL) lower drebrin expression correlates with higher risk of relapse.
Specifications
Applications
FC, WB
Host
Mouse
Clonality
Monoclonal
Clone
DBN-N-03
Isotype
Mouse IgG2b
Supplier
Exbio
Product status
RUO
Shipping & storage
Storage temperature
2-8°C
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Anti-Drebrin Purified
11-694-C100
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Anti-Drebrin Purified
11-694-C100
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