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Anti-Hu CD205 Purified
11-669-C100
0,1 mg
€180
Product description
CD205, also known as DEC-205, is an endocytic receptor of macrophage mannose receptor family. This 205 kDa C-type lectin transmembrane protein mediates adsorptive uptake and its intracellular domain contains coated pit localization sequence and distal acidic motif, which is required for recycling beyond early endosomes through deeper MHC II+ late endosomes and lysosomes. This unique pathway of receptor-mediated uptake proves to be necessary for presentation of antigenic peptides at low doses of ligand. CD205 is responsible for uptake and processing of captured antigens for dendritic cells.
Specifications
Applications
FC, IHC-Fr, WB
Host
Mouse
Clonality
Monoclonal
Clone
HD30
Isotype
Mouse IgG1 kappa
Supplier
Exbio
Product status
RUO
Shipping & storage
Storage temperature
2-8°C
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Anti-Hu CD205 Purified
11-669-C100
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Anti-Hu CD205 Purified
11-669-C100
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