Product description
Grb2 (growth factor receptor-bound protein 2) is a highly conserved adaptor protein composed of central SH2 domain flanked by two terminal SH3 domains. Grb2 mediates coupling of receptor protein tyrosine kinases to a guanine nucleotide exchange factor Sos, thereby enabling the tyrosine kinases to stimulate activity of Ras and hence of MAP kinase pathway. Grb2 also can bind to receptor protein tyrosine phosphatases and affect their signaling.
Specifications
Applications
WB
Host
Rabbit
Clonality
Polyclonal
Clone
PAb (554)
Isotype
Rabbit polyclonal
Supplier
Exbio
Product status
RUO
Shipping & storage
Storage temperature
2-8°C

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Anti-GRB2 Purified

11-554-C100

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Anti-GRB2 Purified

11-554-C100

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