Spz1, a bHLH-zip protein, acts as a proto-oncogene regulated by a MAPK signaling pathway that can increase cell proliferation and tumorigenic activity as well as leading to primary tumor formation (15899793). It is expressed specifically in the testis and epididymis (11165476). Spz1 is a specific binding partner of the gamma2 catalytic subunit of Phosphatase-1c-gamma (PP1c-gamma). The interaction between Spz1 and PP1cgamma2 may be required for proper regulation of spermatogenesis and fertility in males.
Productname
Polyclonal Antibody to SPZ1/TSP1
11-12019
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Productname
Polyclonal Antibody to SPZ1/TSP1
11-12019
By filling out this form, you request a sample. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.
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