Prostaglandin I Synthase Monoclonal Antibody (Clone 3C8)
Prostaglandin I synthase (PGIS) catalyzes the isomerization of PGH2 to PGI2. PGI2 (prostacyclin) is a potent vasodilator and inhibitor of platelet aggregation. PGIS is a membrane-bound hemoprotein localized primarily in endothelial cells.{3476} The cloned bovine and human enzymes contain 500 amino acids and a calculated molecular mass of 56,629 and 57,103, respectively.{3477,3478,3475} Northern blot analysis reveals that the mRNA for PGIS is expressed in a wide variety of human tissues and is particularly abundant in ovary, heart, skeletal muscle, lung, and prostate.{3477}
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Prostaglandin I Synthase Monoclonal Antibody (Clone 3C8)
10247-1
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Prostaglandin I Synthase Monoclonal Antibody (Clone 3C8)
10247-1
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