Product description
The biological effects of prostaglandin E2 (PGE2) are mediated through interaction with four distinct membrane-bound G-protein coupled EP receptors: EP1, EP2, EP3, and EP4.{6742,9114} As a result of splice variation, the EP3 receptor can be expressed as multiple isoforms that differ in the length and sequence of their C-terminal tails.{9114,3180} The signal transduction mechanism varies depending on the isoform being expressed, implicating the importance of the C-terminal region of the receptor for coupling to G-proteins.{9114,3180} The EP3 receptor is expressed in a variety of tissues with highest levels in kidney, pancreas, and uterus.{3180,1610,3179}
Specifications
Applications
IHC, WB, ICC
Host
Rabbit
Clonality
Polyclonal
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C

Price on Request

Productname

EP3 Receptor Polyclonal Antibody

101760-1


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