Product description
Gap-43 is thought to have an important role in development and plasticity because it is expressed at high levels in neuronal growth cones during development and during axonal regeneration.{14428} There is also evidence from knockout animals that Gap-43 serves to amplify path finding signals from the growth cone.{14431} Gap-43 is thought to mediate at least some of these effects via interaction with actin. Importantly, phosphorylation at Ser41 by protein kinase C (Catalog No. 1609-PKC) modulates the interaction of Gap-43 with actin and may also affect neurotransmitter release during forms of plasticity like LTP.{14429,14430}
Specifications
Applications
WB
Host
Rabbit
Clonality
Polyclonal
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C

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Gap-43 (Phospho-Ser41) Polyclonal Antibody

10009400-1

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Gap-43 (Phospho-Ser41) Polyclonal Antibody

10009400-1

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