13(S)-HODE methyl ester

13(S)-hydroxyoctadecadienoic acid (13(S)-HODE) is a 15-lipoxygenase metabolite of linoleic acid produced in endothelial cells, leukocytes, and tumor cells. The biological effects of 13(S)-HODE include inhibition of tumor cell adhesion to the endothelium at concentrations around 1 µM,{592,880} and down regulation of IRGpIIb/IIIa receptor expression.{591} 13(S)-HODE methyl ester is a neutral, more lipophilic form of the free acid that has been used as an analytical standard for 13(S)-HODE.