Prostaglandin F2a-d9

Prostaglandin F2?-d9 (PGF2?-d9) contains nine deuterium atoms at the 17, 17', 18, 18', 19, 19', 20, 20, and 20 positions. It is intended for use as an internal standard for the quantification of PGF2? by GC- or LC-mass spectrometry. PGF2? is a widely distributed PG occurring in many species.{187,421,796} It causes contraction of vascular, bronchial, intestinal, and myometrial smooth muscle, and also exhibits potent luteolytic activity.{187} PGF2? exerts its receptor mediated physiological activity at 50-100 nM.{187} Maximal ovine myometrial contraction can be achieved at 125 nM PGF2? in vitro.{1651}