y-Tocotrienol

?-Tocotrienol is a form of vitamin E that has been found in rice bran and has diverse biological activities.{3679,14290} It reduces cell death induced by hydrogen peroxide, paraquat, S-nitrocysteine, SIN-1 (Item No. 82220), or L-buthionine-(S,R)-sulfoximine (BSO; Item No. 14484) in rat striatal cultures when used at concentrations ranging from 0.1 to 10 µM.{14290} ?-Tocotrienol (20 µM) induces apoptosis in malignant sympathoadrenal (+SA) mouse mammary epithelial cells.{14293} In vivo, ?-tocotrienol (15, 30, and 150 mg/kg) reduces blood pressure and plasma lipid peroxide levels in spontaneously hypertensive rats.{14294} [Matreya, LLC. Catalog No. 2111]