DMPO Nitrone Adduct Polyclonal Antiserum
DMPO is a spin trap that reacts with oxygen-, nitrogen-, sulfur-, and carbon-centered radicals.{2717,10527,3851} It also reacts with DNA base- and amino acid-derived radicals to form DNA- and protein-DMPO nitroxone adducts, respectively, which rapidly decay to form DMPO-nitrone adducts.{55239} DMPO-nitrone adducts were previously detected using electron paramagnetic resonance (EPR), however, immunochemical detection allows a higher level of sensitivity and throughput with greatly reduced sample consumption.{55239,12294,55240} Cayman’s DMPO Nitrone Adduct Polyclonal Antiserum can be used for Western blot, immunocytochemistry, and ELISA applications. The antiserum recognizes various DMPO-nitrone adducts, including DNA and protein species.
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DMPO Nitrone Adduct Polyclonal Antiserum
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