CAY10448
Capsaicin is the primary active component of the heat and pain-eliciting lipid soluble fraction of the Capsicum pepper.{10293} Capsaicin signals are transduced by a heat-activated ion channel, the vanilloid receptor 1 (VR1), or transient receptor potential vanilloid 1 (TRPV1).{5122} CAY10448 is an iodinated nonivamide, a potent capsaicin receptor antagonist with an IC50 value of approximately 10 nM.{12241}
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