Eicosapentaenoic acid-d5 (EPA-d5) is intended for use as an internal standard for the quantification of EPA (Item Nos. 90110 | 90110.1 | 26415) by GC- or LC-MS. EPA is an ?-3 fatty acid abundantly available in marine organisms. It is oxygenated by COX-1 and COX-2 at rates of about 5% and 30%, respectively, compared to arachidonic acid.{16250} EPA has been shown to offer protection against coronary heart disease, thrombosis, ischemic brain injury, scaly dermatitis, and some inflammatory diseases.{32,208}